KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM21A
All Species:
8.18
Human Site:
T448
Identified Species:
22.5
UniProt:
Q641Q2
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q641Q2
NP_001005751.1
1341
147184
T448
S
P
Y
G
P
P
P
T
G
L
F
D
D
D
D
Chimpanzee
Pan troglodytes
XP_001140122
1427
155633
T536
S
P
Y
V
P
P
P
T
G
L
F
D
D
D
D
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534948
1205
132612
R364
E
D
T
E
E
N
T
R
P
K
K
S
R
P
T
Cat
Felis silvestris
Mouse
Mus musculus
Q6PGL7
1334
145292
A439
S
S
H
L
P
T
P
A
G
L
F
D
D
D
D
Rat
Rattus norvegicus
Q80X08
1328
145131
T438
S
P
H
L
P
A
P
T
G
L
F
D
D
D
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001234527
1326
146323
V440
P
K
Q
P
G
K
V
V
L
F
D
D
D
D
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001039320
401
44860
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
A1ZBW7
1469
160880
K532
D
I
D
D
I
F
T
K
P
S
A
Q
P
K
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_800027
2367
254413
V562
I
P
A
G
A
V
N
V
F
G
N
A
G
P
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.3
N.A.
65.9
N.A.
73.5
72.7
N.A.
N.A.
55.4
N.A.
21.7
N.A.
20.4
N.A.
N.A.
24.1
Protein Similarity:
100
92.6
N.A.
70.6
N.A.
80.5
80
N.A.
N.A.
68.7
N.A.
26.2
N.A.
36.6
N.A.
N.A.
36.2
P-Site Identity:
100
93.3
N.A.
0
N.A.
66.6
80
N.A.
N.A.
26.6
N.A.
0
N.A.
0
N.A.
N.A.
13.3
P-Site Similarity:
100
93.3
N.A.
0
N.A.
73.3
86.6
N.A.
N.A.
26.6
N.A.
0
N.A.
0
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
12
0
12
12
0
12
0
0
12
12
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
12
12
12
12
0
0
0
0
0
0
12
56
56
56
56
% D
% Glu:
12
0
0
12
12
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
12
0
0
12
12
45
0
0
0
0
% F
% Gly:
0
0
0
23
12
0
0
0
45
12
0
0
12
0
0
% G
% His:
0
0
23
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
12
12
0
0
12
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
12
0
0
0
12
0
12
0
12
12
0
0
12
12
% K
% Leu:
0
0
0
23
0
0
0
0
12
45
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
12
12
0
0
0
12
0
0
0
0
% N
% Pro:
12
45
0
12
45
23
45
0
23
0
0
0
12
23
0
% P
% Gln:
0
0
12
0
0
0
0
0
0
0
0
12
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
12
0
0
0
0
12
0
0
% R
% Ser:
45
12
0
0
0
0
0
0
0
12
0
12
0
0
0
% S
% Thr:
0
0
12
0
0
12
23
34
0
0
0
0
0
0
12
% T
% Val:
0
0
0
12
0
12
12
23
0
0
0
0
0
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
23
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _